Robert G Gourdie Selected Research

Connexin 43 (Connexin43)

1/2022	Connexin 43 confers chemoresistance through activating PI3K.
12/2021	The Cx43 Carboxyl-Terminal Mimetic Peptide αCT1 Protects Endothelial Barrier Function in a ZO1 Binding-Competent Manner.
5/2021	Peptidic Connexin43 Therapeutics in Cardiac Reparative Medicine.
1/2021	The connexin 43 carboxyl terminal mimetic peptide αCT1 prompts differentiation of a collagen scar matrix in humans resembling unwounded skin.
3/2020	Development of PLGA nanoparticles for sustained release of a connexin43 mimetic peptide to target glioblastoma cells.
1/2019	Interaction of α Carboxyl Terminus 1 Peptide With the Connexin 43 Carboxyl Terminus Preserves Left Ventricular Function After Ischemia-Reperfusion Injury.
1/2019	Cardiomyocyte-myofibroblast contact dynamism is modulated by connexin-43.
1/2018	Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics.
1/2018	Connexin 43-Based Therapeutics for Dermal Wound Healing.
9/2017	Mechanism of action of the anti-inflammatory connexin43 mimetic peptide JM2.

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Robert G Gourdie Research Topics

Disease

14	Wounds and Injuries (Trauma) 01/2021 - 04/2008
10	Cicatrix (Scar) 01/2021 - 04/2008
8	Cardiac Arrhythmias (Arrythmia) 12/2021 - 10/2006
6	Neoplasms (Cancer) 05/2021 - 05/2015
6	Inflammation (Inflammations) 09/2017 - 10/2013
5	Glioblastoma (Glioblastoma Multiforme) 01/2022 - 01/2016
3	Ischemia 01/2020 - 01/2019
3	Myocardial Infarction 10/2016 - 06/2006
2	Edema (Dropsy) 12/2021 - 12/2021
2	Fibrosis (Cirrhosis) 05/2021 - 03/2013
2	Heart Diseases (Heart Disease) 05/2021 - 01/2016
2	Infarction (Infarctions) 01/2019 - 10/2016
2	Hypoxia (Hypoxemia) 01/2019 - 01/2019
2	Ulcer 03/2015 - 01/2015
2	Corneal Injuries 01/2014 - 10/2013
2	Sudden Death 03/2013 - 07/2011
1	Long QT syndrome type 3 12/2021
1	Cardiac Edema 12/2021
1	Stroke (Strokes) 05/2021
1	Reperfusion Injury 01/2019
1	Glioma (Gliomas) 01/2018
1	Foreign-Body Reaction 06/2015
1	Foreign Bodies (Foreign Body) 06/2015
1	Prostatic Neoplasms (Prostate Cancer) 05/2015
1	Diabetic Foot 03/2015
1	Leg Ulcer 01/2015
1	Contracture 10/2014
1	Hypertrophy 11/2011
1	Ventricular Tachycardia 07/2011
1	Epilepsy (Aura) 10/2006
1	Ventricular Remodeling 06/2006
1	Congenital Heart Defects (Congenital Heart Defect) 10/2004

Drug/Important Bio-Agent (IBA)

25	Connexin 43 (Connexin43)IBA 01/2022 - 10/2006
17	Peptides (Polypeptides)IBA 01/2022 - 03/2009
10	ConnexinsIBA 01/2022 - 03/2011
4	Pharmaceutical PreparationsIBA 05/2021 - 01/2014
3	Temozolomide (Temodar)FDA LinkGeneric 01/2022 - 01/2016
3	SodiumIBA 12/2021 - 01/2019
3	CalciumIBA 01/2020 - 01/2017
3	Poloxamer (Poloxamer 407)IBA 06/2015 - 10/2013
2	CollagenIBA 01/2021 - 10/2014
2	Proteins (Proteins, Gene)FDA Link 10/2016 - 03/2015
2	Capsules (Microcapsules)IBA 01/2014 - 10/2013
1	Phosphotransferases (Kinase)IBA 01/2022
1	Messenger RNA (mRNA)IBA 01/2022
1	Voltage-Gated Sodium ChannelsIBA 12/2021
1	Amino Acids FDA Link 03/2020
1	Delayed-Action PreparationsIBA 03/2020
1	10-N-nonylacridinium orange (NAO)IBA 01/2019
1	erucylphosphocholineIBA 01/2019
1	Anti-Arrhythmia AgentsIBA 01/2019
1	Mannitol (Osmitrol)FDA LinkGeneric 01/2019
1	AlbuminsIBA 01/2019
1	AcidsIBA 01/2019
1	PeptidomimeticsIBA 01/2018
1	Ion Channels (Ion Channel)IBA 10/2016
1	Biomarkers (Surrogate Marker)IBA 01/2016
1	Sodium Channels (Sodium Channel)IBA 10/2015
1	Flecainide (Tambocor)FDA LinkGeneric 10/2015
1	Protein Isoforms (Isoforms)IBA 06/2015
1	Adenosine Triphosphate (ATP)IBA 06/2015
1	SiliconesIBA 06/2015
1	Streptozocin (Streptozotocin)FDA Link 01/2014
1	polyornithineIBA 01/2014
1	AlginatesIBA 01/2014
1	Therapeutic UsesIBA 01/2014
1	SolutionsIBA 01/2014
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 11/2011
1	Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA 07/2011
1	Serine (L-Serine)FDA Link 05/2011
1	A-factor (Streptomyces)IBA 10/2006
1	Matrix Metalloproteinase 7 (Matrilysin)IBA 06/2006
1	Matrix Metalloproteinases (MMPs)IBA 06/2006
1	Transcription Factors (Transcription Factor)IBA 10/2004

Therapy/Procedure

11	Therapeutics 01/2019 - 04/2008
1	Drug Therapy (Chemotherapy) 01/2022
1	Occlusive Dressings (Occlusive Dressing) 01/2017
1	Rejuvenation 10/2016
1	Topical Administration 03/2015
1	Compression Bandages 01/2015
1	Ligation 01/2013